Table 2

HRs from Cox multivariate models

VariableStrataHR95% CIp Value
Multivariate regression of NI vs RoI
Age at diagnosisPer 10 year increase1.41.32 to 1.58<0.001
Diagnostic delay<31 weeks1
31–55 weeks0.960.78 to 1.200.745
>55 weeks0.660.52 to 0.83<0.001
CountryNI1
RoI0.720.59 to 0.870.001
SexFemale1
Male1.070.89 to 1.300.460
Site of onsetLimb1
Bulbar1.060.85 to 1.310.611
Both1.730.64 to 4.710.283
Riluzole useNo1
Yes0.610.48 to 0.78<0.001
GastrostomyNo1
Yes0.980.78 to 1.240.893
NIVNo1
Yes1.231.00 to 1.510.048
Multivariate regression of MDT care vs general care
Age at diagnosisPer 10 year increase1.401.28 to 1.53<0.001
Diagnostic delay<31 weeks1
31–55 weeks0.960.77 to 1.190.685
>55 weeks0.670.53 to 0.840.001
MDTNo1
Yes0.590.49 to 0.71<0.001
SexFemale1
Male1.020.84 to 1.240.829
Site of onsetLimb1
Bulbar1.040.84 to 1.290.701
Both1.800.66 to 4.890.249
Riluzole useNo1
Yes0.680.54 to 0.870.002
GastrostomyNo1
Yes0.900.71 to 1.130.355
NIVNo1
Yes1.381.12 to 1.690.003
  • MDT, multidisciplinary team; NI, Northern Ireland; NIV, non-invasive ventilation; RoI, Republic of Ireland.