Table 1

Baseline characteristics and results

No.Male/female (No.)Age (year) (range)BMI (range)Mean ANG serum level (ng/mL)SDp Value
ALS265148/11763 (23–84)24.7 (17.3–37.6)425.3111.31.74×10−3
 Bulbar ALS8740/4766 (41–84)24.4 (17.3–35.1)410.9115.50.02
 Spinal ALS178112/6661 (23–83)24.7 (17.5–37.6)433.2109.52.90×10−3
PD163112/5164 (34–88)25.0 (15.9–41.1)399.776.40.72
Controls462254/20868 (33–95)26.9 (16.6–37.7)401.695.9
  • Age is at sample collection, BMI, body mass index, p values were calculated using ANCOVA with age, gender, BMI as covariates. Also see online supplementary figure S1 and supplementary table S1.

  • ALS, amyotrophic lateral sclerosis; ANCOVA, analysis of covariance; ANG, angiogenin; PD, Parkinson's disease.