Table 1

Underlying causes of catatonia (other than schizophrenia and mood disorder)

Infections
 Typhoid fever
 Neurocysticercosis
 Prion disease
 Viral encephalitis
 Subacute sclerosing pan encephalitis
 Neurosyphilis
Autoimmune and inflammatory
 Systemic lupus erythymatosis or antiphospholipid syndrome*
 Anti-NMDAR encephalitis*
 Paraneoplastic encephalitis
 Multiple sclerosis
Cardiovascular
 Takotsubo cardiomyopathy
Renal
 Renal failure in dementia with Lewy body disease
Metabolic
 Wilson's disease
 Hyponatraemia or hypernatraemia
 Glucose-6phosphate deficiency
Neurodegenerative disorders
 Westphal variant of Huntington's disease
 Parkinson's disease
 Familial frontotemporal dementia
CNS
 Posterior reversible encephalopathy
 Subdural hematoma
 Pontine and extrapontine myelinolysis
 Stroke
Hematology
 Pernicious anemia
 Thrombotic thrombocytopenic purpura
Psychiatric
 Autism*
 Alcohol withdrawal
Medications
 Venlafaxine-associated hyponatraemia
 Pegylated interferon-α 2b and ribavirin for hepatitis C
 Lorazepam withdrawal
 Paliperidone palmitate
 Dexamethasone
 Zolpidem withdrawal
 Temazepam withdrawal
 Quinolones
 Clozapine withdrawal*
 Manganese neurotoxicity
 Clonazepam/benzodiazepine withdrawal
 Ziprasidone
 Lithium toxicity
 Tramadol and meperidine
 Azithromycin
 Levetiracetam
 Efavirenz
Surgical causes
 Liver or kidney transplantation*
 Renal transplant
 Temporal lobectomy
 Deep brain stimulation surgery
 Burns
 Trauma
Other causes
 Cyber bulling
 Deprivation, abuse or trauma in pediatric population
 Pregnancy or postpartum
 Down syndrome
 Wasp sting
  • *Most frequently reported causes of catatonia.

  • Anti-NMDAR, anti-N-Methyl-d-aspartate; CNS, central nervous system.