Table 1

Baseline characteristics and outcome of 88 patients, n (%) if not indicated otherwise

Non-thrombolysed patientsThrombolysed patientsp Value comparing the two groups
N4741
Age, years (SD)68 (14.1)66.3 (12.9)0.831
Women14/47 (29.8)19/41 (46.3)0.110
Vascular risk factors
 Diabetes mellitus10/47 (21.3)9/41 (22)0.939
 Arterial hypertension29/47 (61.7)25/41 (61)0.944
 Current smoking13/47 (27.7)9/39 (23.1)0.628
 Hypercholesterolaemia31/47 (66)27/41 (65.9)0.992
 Coronary artery disease8/47 (17)7/41 (17.1)0.995
 Atrial fibrillation8/40 (20)14/37 (37.8)0.083
 Previous stroke1/47 (2.1)2/41 (4.9)0.478
 Cervical artery dissection8/47 (17)2/41 (4.9)0.073
 Family history of stroke10/29 (34.5)6/32 (18.8)0.163
Aetiology according to TOAST criteria0.086
 Large artery disease17/47 (36.2)9/41 (22)0.214
 Cardioembolic8/47 (17)16/41 (39)0.021
 Other determined9/47 (19.2)3/41 (7.3)0.107
 Undetermined3/47 (6.4)5/41 (12.2)0.344
 Unknown5/47 (10.6)6/41 (14.6)0.572
 More than one potential cause5/47 (10.6)2/41 (4.9)0.319
Minutes from symptom onset to hospital admission, median258101<0.001
Improving symptoms before admission22/47 (46.8)18/40 (45)0.866
Fluctuating symptoms before admission15/47 (31.9)9/40 (22.5)0.327
Baseline NIHSS score, median (range)3 (5)4 (3)<0.001
Imaging parameters
Location of vessel occlusion<0.001
 ICA occlusion35/47 (74.5)12/41 (29.3)
 M1 occlusion12/47 (25.5)29/41 (70.7)
MR mismatch27/35 (77.1)30/30 (100)0.005
Thrombolysis type
 Intravenous rt-PA15*/41 (36.6)
 Endovascular therapy19/41 (46.3)
 Bridging (intravenous rt-PA followed by endovascular therapy)7/41 (17.1)
  • *Out of these patients 2 were initially intended for bridging therapy.

  • A p value of <0.05 was considered significant, these are in bold font.

  • ICA, internal carotid artery; NIHSS, National Institutes of Health Stroke Scale; TOAST, Trial of ORG 10172 in Acute Stroke Treatment.