≥50% First-time responders, variable | OnabotulinumtoxinA (n=688) | ||
---|---|---|---|
Treatment cycle 1 | Treatment cycle 2 | Treatment cycle 3 | |
Frequency of headache days, n (%) | 339 (49.3) | 78 (11.3) | 71 (10.3) |
95% CI | 45.5% to 53.0% | 9.0% to 13.7% | 8.1% to 12.6% |
Frequency of moderate/severe headache days, n (%) | 365 (53.1) | 90 (13.1) | 59 (8.6) |
95% CI | 49.3% to 56.8% | 10.6% to 15.6% | 6.5% to 10.7% |
Total cumulative hours of headache on headache days, n (%) | 373 (54.2) | 80 (11.6) | 51 (7.4) |
95% CI | 50.5% to 57.9% | 9.2% to 14.0% | 5.5% to 9.4% |
*First-time responders for a given time point are patients who never responded at any previous time points.