Table 1

Demographics, clinical characteristics and apraxia scores

AD*bvFTD*HC*AD vs HC†bvFTD vs HC†bvFTD vs AD†
Demographics
 Age (years)69.8(10.5)66.6(8.1)63.7(9.4)6.152.95−3.20
 Education (years)11.0(1.8)11.4(1.9)11.9(1.9)−0.90−0.500.40
 Females/N13/20 4/208/20N/AN/AN/A
Disease severity scores
 MMSE score22.4(2.2)25.4(3.5)29.0(1.0)−6.60‡−3.65‡2.95‡
 Disease duration (months)§19.1(8.9)33.3(21.3)N/AN/AN/A14.21‡
 FBI score§11.1(6.2)34.4(12.3)N/AN/AN/A23.31‡
Apraxia composite scores
 CAS score total (maximum 80)62.8(11.8)66.5(5.4)76.9(2.2)−14.10−10.403.70
 IAT score total (maximum 30)15.5(7.6)18.6(5.6)24.4(2.9)−8.90−5.753.15
 MI score total (maximum 24)16.0(5.0)18.4(2.9)21.9(1.8)−5.90−3.502.40
Apraxia subdomain scores (% correct gestures)
 Imitation (all)63.1(20.2)71.0(11.9)88.8(5.4)−25.70−17.737.97
 Pantomime (all)83.1(14.2)88.1(7.2)97.3(2.9)−14.17−9.175.00
 Pantomime of object use81.4(16.1)88.6(7.2)97.5(3.2)−16.13−8.887.25
 Pantomime of emblems91.9(10.2)85.6(17.8)96.3(8.2)−4.38−10.63‡−6.25
 Imitation (hand and fingers)55.5(25.0)71.7(13.8)86.7(7.1)−31.21−15.0816.14‡
 Imitation (face)88.0(15.1)69.0(20.2)95.5(8.3)−7.50−26.50−19.00
  • bold indicate significant differences at p<0.0056 (Bonferroni correction for number of apraxia variables).

  • *Reported values in this column are means and SD (in parentheses).

  • †Reported values in this column are mean difference scores.

  • ‡significant group differences at p<0.05.

  • §Data available from 18/20 patients with bvFTD and 15/20 patients with AD.

  • AD, Alzheimer's dementia; bvFTD, behavioural variant frontotemporal dementia; CAS, Cologne Apraxia Screening; FBI, Frontal Behavioural Inventory; HC, healthy controls; IAT, Ideomotor Apraxia Test; MI, Münster apraxia items; MMSE, Mini-Mental State Examination; N/A, not applicable.