Table 3

MRI and VEP findings in 40 patients with CCPD

n/N (%)
MRI
 Cerebral lesions30/40 (75.0)
  ≤36/30 (20.0)
  4–813/30 (43.3)
  ≥911/30 (36.7)
  Gd-enhancement7/40 (17.5)
  Lesions larger than 3 cm10/40 (25.0)
 Cerebellar lesions6/40 (15.0)
  Gd-enhancement2/40 (5.0)
 Brainstem lesions13/40 (32.5)
  Gd-enhancement3/40 (7.5)
 Optic nerve lesions7/40 (17.5)
  Gd-enhancement1/40 (2.5)
 Spinal cord lesions30/40 (75.0)
  LESCLs3/40 (7.5)
  Gd-enhancement11/40 (27.5)
VEPs
 Abnormal findings15/21 (71.4)
  Right2/15 (13.3)
  Left5/15 (33.3)
  Bilateral8/15 (53.3)
Affected CNS sites
 Brain only4/40 (10.0)
 Optic nerves only1/40(2.5)
 Spinal cord only7/40 (17.5)
 Brain+optic nerves5/40 (12.5)
 Brain+spinal cord13/40 (32.5)
 Optic nerves+spinal cord2/40 (5.0)
 Brain+optic nerves+spinal cord8/40 (20.0)
  • CCPD, combined central and peripheral demyelination; CNS, central nervous system; Gd, gadolinium; LESCLs, longitudinally extensive spinal cord lesions; N, number of cases collated; N, number of involved cases; VEPs, visual-evoked potentials.