Performance of patients with AFF− (n=12) and AFF+ (n=21) on behavioural measures
| Measure | AFF- z>2SD n (%) | AFF+ z>2SD n (%) | Fisher's exact test, p value (2-sided/1-sided) |
|---|---|---|---|
| IRI patient (n=24) | |||
| Total score | 0 | 3 (14.3) | 0.53/0.28 |
| PT | 1 (8.3) | 3 (14.3) | 1.0/0.54 |
| FS | 2 (16.7) | 3 (14.3) | 1.0/0.56 |
| EC | 0 | 2 (9.5) | 0.52/0.40 |
| PD | 0 | 0 | – |
| IRI informant (n=22) | |||
| Total score | 0 | 2 (9.5) | 0.52/0.39 |
| PT | 1 (8.3) | 2 (9.5) | 1.0/0.71 |
| FS | 1 (8.3) | 1 (4.8) | 1.0/0.61 |
| EC | 1 (8.3) | 1 (4.8) | 1.0/0.59 |
| PD | 0 | 0 | – |
| FrSBe patient (n=25) | |||
| Total score | 3 (25) | 2 (9.5) | 0.31/0.23 |
| Apathy | 5 (41.7) | 2 (9.5) | 0.058/0.034 |
| Disinhibition | 2 (16.7) | 4 (19) | 1.0/0.64 |
| EF | 1 (8.3) | 1 (4.8) | 1.0/0.60 |
| FrSBe informant (n=23) | |||
| Total score | 0 | 3 (14.3) | 0.53/0.26 |
| Apathy | 1 (8.3) | 2 (9.5) | 1.0/0.73 |
| Disinhibition | 0 | 4 (19) | 0.26/0.15 |
| EF | 0 | 3 (14.3) | 0.53/0.26 |
Behavioural measures are all current, post-illness ratings; Performance of >2 SD than control mean for FrSBe measures indicates abnormality, while for IRI, abnormality is defined by performance <2 SD, indicating less empathy; For Informant z-scores, healthy control data from ‘current self-ratings’ was used.
AFF−, patients with impaired Affective ToM; AFF+, patients with unimpaired Affective ToM; EC, empathic concern; EF, executive dysfunction; FrSBe, Frontal Systems Behavior Scale; FS, fantasy; IRI, Interpersonal Reactivity Index; PD, personal distress; PT, perspective-taking; ToM, Theory of Mind.