Demographic and clinical data of control subjects and patient groups
| Control | Sporadic amyotrophic lateral sclerosis | Amyotrophic lateral sclerosis patients homozygous for aspartate-to-alanine mutations in codon 90 | |
| N | 20 | 20 | 7 |
| Gender (male:female) | 12:8 | 14:6 | 1:6 |
| Age (years) | 53±16 | 56±11 | 50±11 |
| Site of disease onset | NA | 16 limb | 7 limb |
| 4 bulbar | |||
| Disease duration (months) | NA | 28±18 | 42±47 |
| Amyotrophic lateral sclerosis functional rating scale | NA | 38±6 | 37±7 |
| Ashworth spasticity score | NA | 2±3 | 9±2 |
| Upper motor neuron burden score | NA | 8±6 | 9±2 |