Stroke risk associated with stress resilience and other characteristics
| Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|
| Events/n | Model 1 HR (95% CI) | Model 2 HR (95% CI) | Model 3 HR (95% CI) | Model 4 HR (95% CI) | |
| Stress resilience | |||||
| 1. High (7–9) | 690/56 293 | Reference | Reference | Reference | Reference |
| 2. Moderate (4–6) | 1751/129 746 | 1.09 (1.00 0 to 1.19) | 1.07 (0.98 to 1.16) | 1.01 (0.92 to 1.10) | 0.94 (0.86 to 1.03) |
| 3. Low (1–3) | 970/51 840 | 1.54 (1.40 to 1.70) | 1.48 (1.34 to 1.63) | 1.30 (1.18 to 1.45) | 1.16 (1.04 to 1.29) |
| Parental SEI 1960 | |||||
| Manual workers | 1527/98 845 | 1.21 (1.11 to 1.31) | 1.14 (1.04 to 1.24) | 1.08 (0.98 to 1.18) | 1.06 (0.97 to 1.16) |
| Agricultural workers | 129/9227 | 1.08 (0.90 to 1.30) | 1.00 (0.82 to 1.20) | 0.92 (0.76 to 1.09) | 0.90 (0.74 to 1.09) |
| Farm owners/managers | 321/23 741 | 1.03 (0.91 to 1.17) | 1.02 (0.89 to 1.16) | 0.96 (0.84 to 1.10) | 0.96 (0.84 to 1.10) |
| Office workers | 836/65 896 | Reference | Reference | Reference | Reference |
| Business/owners managers | 349/25 500 | 1.08 (0.95 to 1.22) | 1.06 (0.93 to 1.20) | 1.03 (0.91 to 1.17) | 1.02 (0.90 to 1.15) |
| Others/unknown | 249/14 580 | 1.35 (1.17 to 1.56) | 1.24 (1.08 to 1.44) | 1.18 (1.02 to 1.36) | 1.16 (1.01 to 1.34) |
| Household crowding, 1960 | |||||
| ≤2 people/room | 2543/185 792 | Reference | Reference | Reference | Reference |
| >2 people/room | 868/52 087 | 1.22 (1.13 to 1.32) | 1.15 (1.06 to 1.24) | 1.12 (1.03 to 1.21) | 1.11 (1.03 to 1.20) |
| Cognitive function (per unit change, 1–9) | 0.92 (0.90 to 0.93) | 0.94 (0.92 to 0.95) | 0.94 (0.93 to 0.97) | ||
| Diastolic blood pressure (per 1 mm Hg change) | 1.02 (1.01 to 1.02) | 1.02 (1.01 to 1.02) | 1.01 (1.01 to 1.02) | ||
| Systolic blood pressure (per 1 mm Hg change) | 1.01 (1.01 to 1.01) | 1.01 (1.00 to 1.01) | 1.00 (1.00 to 1.01) | ||
| CVD diagnosis | |||||
| Yes | 107/6631 | 1.13 (0.94 to 1.38) | 1.10 (0.90 to 1.33) | 1.09 (0.90 to 1.32) | |
| No | 3304/231 248 | Reference | Reference | Reference | |
| Physical working capacity (per unit change, 0–9) | 0.91 (0.90 to 0.93) | 0.92 (0.90 to 0.94) | |||
| Body Mass Index (kg/m2) | |||||
| Underweight (<18.49) | 374/27 657 | 0.99 (0.89 to 1.01) | 0.85 (0.76 to 0.95) | ||
| Normal weight (18.5–24.99) | 2636/192 213 | Reference | Reference | ||
| Overweight (25.0–29.99) | 321/15 615 | 1.51 (1.34 to 1.69) | 1.45 (1.29 to 1.63) | ||
| Obese (≥30.0) | 80/2394 | 2.52 (2.02 to 3.15) | 2.14 (1.71 to 2.68) | ||
Model 1. Unadjusted.
Model 2. Adjusted for socio/material background factors (birth year, region, parental SEI and household crowding).
Model 3. Adjusted for 2+ characteristics in adolescence (cognitive function, diastolic and systolic blood pressure and CVD diagnosis at conscription).
Model 4. Adjusted for 2+3+ physical fitness in adolescence (physical working capacity and BMI).
CVD, cardiovascular disease; SEI, socioeconomic index.