NTD | Facial cleft | Cardiac | Hypospadias/GUT | GIT | Skeletal | Other | Total | |
---|---|---|---|---|---|---|---|---|
Valproate (total 1220) | 13 (1.1%) | 13 (1.1%) | 14 (1.1%) | 15 (1.2%) | 7 (0.6%) | 10 (0.8%) | 10 (0.8%) | 82 |
Carbamazepine (total 1657) | 4 (0.2%) | 4 (0.2%) | 14 (0.8%) | 5 (0.3%) | 5 (0.3%) | 4 (0.2%) | 7 (0.4%) | 43 |
Lamotrigine (total 2098) | 2 (0.1%) | 2 (0.1%) | 9 (0.4%) | 10 (0.5%) | 8 (0.4%) | 3 (0.1%) | 15 (0.7%) | 49 |
AED, antiepileptic drug; GIT, gastrointestinal tract defect; GUT, genitourinary tract defect; NTD, neural tube defect.