Best fitting Cox proportional hazards model showing independent predictors of survival at initial visit
| Predictor variable | HR | 95% CI | p Value |
|---|---|---|---|
| Age(year) | |||
| <70 | 1 | ||
| ≥70 | 1.44 | 0.99 to 2.11 | 0.060 |
| Site of onset | |||
| Limb | 1 | ||
| Bulbar | 1.62 | 1.13 to 2.33 | <0.05 |
| ΔFS tertiles | |||
| <0.47 | 1 | ||
| 0.47–1.11 | 1.63 | 1.09 to 2.26 | <0.05 |
| >1.11 | 3.05 | 1.93 to 4.83 | <0.001 |
The rate of disease progression (ΔFS) and site of onset were independent predictors of survival in amyotrophic laterals sclerosis.