Baseline characteristics
| Variable | All patients N=63* |
|---|---|
| Sex, n (%) | |
| Female | 52 (82.5) |
| Male | 11 (17.5) |
| Type of MS, n (%) | |
| RRMS | 61 (96.8) |
| CIS | 2 (3.2) |
| Age, mean±SD, years | 38±9.8 |
| Age at disease diagnosis, mean±SD, years | 32±8.3 |
| Disease duration, mean±SD, years | 8±7.9 |
| EDSS, mean±SD | 2±1.5 |
| SIENAX absolute BV, mean±SD (minimum–maximum), mL | 1101±109.0 (853–1393) |
| NeuroQuant absolute BV, mean±SD (minimum–maximum), mL | 1162±118.0 (902–1468) |
| MSmetrix absolute BV, mean±SD (min–max), mL | 1107±103.0 (881–1364) |
| T2 lesion number, mean±SD (minimum–maximum) | 51±38.2 (4–159) |
| T2 lesion volume, mean±SD (min–max), mL | 7±8.2 (0.1–32) |
*Three participants were excluded from the MSmetrix analysis.
BV, brain volume; CIS, clinically isolated syndrome; EDSS, Expanded Disability Status Scale; MS, multiple sclerosis; RRMS, relapsing-remitting multiple sclerosis; SIENAX, Structural Image Evaluation using Normalisation of Atrophy-Cross-sectional.