Table 3

eQTL data for the 7 SNPs associated with rapid decline on ALSFRS-R

rsIDChrPositionLowest eQTL p valueProbe gene
rs120529832179 361 8814.12×10−8TTN
rs21145822179 287 8347.35×10−8TTN
rs23035372179 366 0931.07×10−7TTN
rs48940202179 288 6901.44×10−8TTN
rs67537092179 319 3911.44×10−8TTN
rs76001762179 324 0251.60×10−8TTN
rs9578752179 384 4178.60×10−10TTN
  • ALSFRS-R, amyotrophic lateral sclerosis functional rating scale; chr, chromosome; eQTL, expression quantitative trait loci; SNP, single nucleotide polymorphism.