Table 1

Demographic data of patients with ALS from various Asia-Pacific countries based on population-based and cohort studies

Study locationType of studyNumber of patients with ALSEthnicityPrevalence (per 105)Incidence (per 105)Mean age of onsetGender ratio (M:F)Survival (months)
AustraliaNational Disease and Mortality Registry*861138Caucasian82.74611.527
ChinaPopulation-based9120Han Chinese30.658.761.72
Population-based8784Han Chinese0.950.3551.95
Single-centre cohort131624Han Chinese49.81.771 (median)
Multicentre cohort15455Han Chinese52.41.63
Single-centre cohort141131Han Chinese54.31.45
IndiaSingle-centre cohort and population-based study10 161153South Indian446.23114.8
JapanNational survey710 231Japanese9.92.2
Multicentre cohort11451Japanese61.21.8748 (TPPV-free)
Population-based88389Japanese2.250.69
Population-based8977Japanese1.4361.82.9
Population-based90134Japanese11.32.564.71.43
MalaysiaSingle-centre cohort6973Chinese, Malays, Indians51.51.4344.9
New ZealandPopulation-based91244Caucasian6.72.2564.61.227.6
South KoreaMulticentre cohort†12373Korean2.81.78581.5
TaiwanMulticentre cohort8783Han Chinese1.970.51.67
Multicentre cohort711149Han Chinese1.2767.8
  • *Demographic information for Australia was derived from both Patient Registry database and the National Mortality Register.

  • †Demographic information from South Korea was derived both from a multicentre cohort study and Patient Registry database through personal communication.

  • ALS, amyotrophic lateral sclerosis; F, female; M, male; TPPV, tracheostomy positive pressure ventilation.