Table 2

Univariate analysis of clinical and demographic predictors of NRS IR at T1 in a population of 1432 patients

Univariate analysis T1
IR+
N=1010
IR−
N=422
OR95% CIp Value
Sex
 Women (%)540 (53.5)214 (50.7)1NANA
 Men (%)469 (46.4)208 (49.3)0.890.7 to 1.10.324
Age (years, mean. Median=51)50.8±9.651.2±9.60.990.98 to 1.00.471
 18/51539 (53.4)242 (57.3)1NANA
 51/99471 (46.6)180 (42.6)0.980.78 to 1.230.893
Disease duration (years, mean. Median=17)17.8±8.617.4±8.61.00.99 to 1.010.416
 0/17518 (51.3)212 (50.2)1NANA
 >17492 (48.7)210 (49.8)0.930.74 to 1.170.552
EDSS (years, mean. Median=6.5)6.5±1.16.5±1.21.020.92 to 1.120.686
 0–6.5607 (60)245 (58)1NANA
 >6.5403 (39.9)177 (41.9)0.970.77 to 1.220.806
Multiple sclerosis type
 Relapsing remitting188 (18.6)74 (17.5)1NANA
 Secondary progressive and primary progressive822 (81.4)348 (82.4)1.41.05 to 1.860.018
NRS (score, mean. Median=8)7.6±1.47.3±1.51.21.1 to 1.3<0.001
 4/8752 (74.5)322 (76.3)1NANA
 >8258 (25.5)100 (23.7)1.81.4 to 2.4<0.001
  • EDSS, expanding disability status scale; IR, initial response; NA, not applicable; NRS, numerical rating scale.