All ICH | Lobar ICH | Deep ICH | ||||
---|---|---|---|---|---|---|
OR (95% CI) | p Value | OR (95% CI) | p Value | OR (95% CI) | p Value | |
Age, years | 1.004 (0.99 to 1.009) | 0.100 | 1.00 (0.99 to 1.01) | 0.302 | 1.00 (0.99 to 1.01) | 0.264 |
Hypertension | ||||||
Non-hypertensive | 1 | 1 | 1 | |||
Hypertensive under treatment | 1.55 (1.37 to 1.74) | <0.001 | 1.23 (1.03 to 1.47) | 0.018 | 1.86 (1.58 to 2.19) | <0.001 |
Hypertensive not under treatment | 9.46 (7.41 to 12.0) | <0.001 | 6.43 (4.45 to 9.29) | <0.001 | 12.51 (8.98 to 17.42) | <0.001 |
Diabetes | ||||||
Non-diabetic | 1 | 1 | 1 | |||
Diabetic under treatment | 1.18 (1.01 to 1.39) | 0.035 | 1.15 (0.90 to 1.47) | 0.249 | 1.19 (0.96 to 1.48) | 0.100 |
Diabetic not under treatment | 2.47 (1.63 to 3.74) | <0.001 | 2.30 (1.23 to 4.30) | 0.009 | 2.58 (1.47 to 4.53) | 0.001 |
Cholesterolaemia | ||||||
Non-hypercholesterolaemic | 1 | 1 | 1 | |||
Hypercholesterolaemic under treatment with statins | 0.79 (0.68 to 0.93) | 0.006 | 0.85 (0.67 to 1.07) | 0.184 | 0.75 (0.60 to 0.93) | 0.011 |
Hypercholesterolaemic not under treatment | 0.44 (0.37 to 0.52) | <0.001 | 0.39 (0.30 to 0.52) | <0.001 | 0.46 (0.37 to 0.58) | <0.001 |
Alcohol, heavy intake | 1.079 (0.92 to 1.26) | 0.335 | 0.89 (0.69 to 1.13) | 0.346 | 1.26 (1.03 to 1.55) | 0.024 |
Current smoking | 1.10 (0.94 to 1.30) | 0.222 | 1.04 (0.81 to 1.35) | 0.346 | 1.13 (0.91 to 1.40) | 0.251 |
Antiplatelet agents | 3.24 (2.83 to 3.70) | <0.001 | 3.59 (2.94 to 4.37) | <0.001 | 3.05 (2.54 to 3.66) | <0.001 |
Oral anticoagulants | 19.13 (13.08 to 27.98) | <0.001 | 25.33 (13.98 to 42.34) | <0.001 | 15.67 (9.26 to 26.49) | <0.001 |
Multivariable model controlled for age, hypertension, diabetes mellitus, hypercholesterolaemia, current smoking, alcohol consumption and antithrombotic medications.
ICH, intracerebral haemorrhage.