Table 2

Multivariable ORs for intracerebral haemorrhage by location

All ICHLobar ICHDeep ICH
OR (95% CI)p ValueOR (95% CI)p ValueOR (95% CI)p Value
Age, years1.004 (0.99 to 1.009)0.1001.00 (0.99 to 1.01)0.3021.00 (0.99 to 1.01)0.264
Hypertension
 Non-hypertensive111
 Hypertensive under treatment1.55 (1.37 to 1.74)<0.0011.23 (1.03 to 1.47)0.0181.86 (1.58 to 2.19)<0.001
 Hypertensive not under treatment9.46 (7.41 to 12.0)<0.0016.43 (4.45 to 9.29)<0.00112.51 (8.98 to 17.42)<0.001
Diabetes
 Non-diabetic111
 Diabetic under treatment1.18 (1.01 to 1.39)0.0351.15 (0.90 to 1.47)0.2491.19 (0.96 to 1.48)0.100
 Diabetic not under treatment2.47 (1.63 to 3.74)<0.0012.30 (1.23 to 4.30)0.0092.58 (1.47 to 4.53)0.001
Cholesterolaemia
 Non-hypercholesterolaemic111
 Hypercholesterolaemic under treatment with statins0.79 (0.68 to 0.93)0.0060.85 (0.67 to 1.07)0.1840.75 (0.60 to 0.93)0.011
 Hypercholesterolaemic not under treatment0.44 (0.37 to 0.52)<0.0010.39 (0.30 to 0.52)<0.0010.46 (0.37 to 0.58)<0.001
Alcohol, heavy intake1.079 (0.92 to 1.26)0.3350.89 (0.69 to 1.13)0.3461.26 (1.03 to 1.55)0.024
Current smoking1.10 (0.94 to 1.30)0.2221.04 (0.81 to 1.35)0.3461.13 (0.91 to 1.40)0.251
Antiplatelet agents3.24 (2.83 to 3.70)<0.0013.59 (2.94 to 4.37)<0.0013.05 (2.54 to 3.66)<0.001
Oral anticoagulants19.13 (13.08 to 27.98)<0.00125.33 (13.98 to 42.34)<0.00115.67 (9.26 to 26.49)<0.001
  • Multivariable model controlled for age, hypertension, diabetes mellitus, hypercholesterolaemia, current smoking, alcohol consumption and antithrombotic medications.

  • ICH, intracerebral haemorrhage.