Table 1

Correlations with seizure burden for the PWMB and CB

Correlation with seizure burden
IpsilateralContralateral
ParameterROIPearson's rp ValuePearson's rp Value
Parahippocampal white matter bundle
MD10.2720.1960.3100.150
20.4420.038*0.2790.197
30.6020.007*0.3420.129
40.5320.017*0.3860.083
50.4570.036*0.2770.197
FA1−0.1220.547−0.0890.665
2−0.2140.304−0.1660.430
3−0.2460.238−0.2850.192
4−0.2020.329−0.1300.542
50.1380.502−0.1900.369
MK10.1200.5490.1740.408
20.3250.1320.2040.339
30.4840.027*0.4360.050*
40.3970.0700.3960.076
50.2330.2620.3290.142
KFA1−0.2580.212−0.2530.236
2−0.4590.036*−0.3360.135
3−0.6230.006*−0.4650.035*
4−0.5640.009*−0.4520.039*
5−0.3060.148−0.3130.147
Cingulum bundle
MD10.3360.1260.0990.622
20.3140.1400.1870.364
30.3160.1380.1760.390
40.3860.0750.2610.209
50.4460.037*0.3310.132
FA1−0.2120.305−0.0600.765
2−0.2840.178−0.0030.986
3−0.3380.1270.0240.908
4−0.3580.098−0.2190.296
5−0.3030.150−0.3900.073
MK10.4150.0540.3940.071
20.5180.019*0.5660.010*
30.4540.035*0.5920.007*
40.4560.035*0.4770.029*
50.4890.026*0.5040.022*
KFA1−0.4650.034*−0.3170.140
2−0.4980.023*−0.3660.090
3−0.5150.019*−0.3060.150
4−0.6230.011*−0.3800.078
5−0.5820.008*−0.5250.018*
  • ROI numbers correspond to the ROIs depicted in figure 2, and statistically significant correlations are indicated by bold font and asterisks for p<0.05 after FDR correction for multiple comparisons.

  • CB, cingulum bundle; FA, fractional anisotropy; FDR, false discovery rate; KFA, kurtosis fractional anisotropy; MD, mean diffusivity; MK, mean kurtosis; PWMB, parahippocampal white matter bundle; ROI, region of interest.