Table 3

Inter-rater agreement for all significant lesion characteristics, expressed as median and range of κ's between all sets of raters

Lesion characteristicsMedian κ between sets of ratersRange of κ's
General characteristics
 Lesion size >3 cm0.520.18–0.70
Tissue involvement
 Juxtacortical WM0.720.44–0.87
 Periventricular WM0.590.47–0.84
 Cortical GM0.220.13–0.35
Lesion appearance
 Focal lesion appearance0.560.38–0.82
Lesion borders
 Lesion border towards WM0.19−0.24–0.66
 Lesion border towards GM0.091−0.092–0.25
Specific PML characteristics
 Presence of punctate T2 lesions0.570.49–0.67
MRI sequences and contrast enhancement
 Presence of contrast enhancement0.780.55–0.87
  • FLAIR, fluid-attenuated inversion recovery; GM, grey matter; PML, progressive multifocal leukoencephalopathy; WM, white matter.