Inter-rater agreement for all significant lesion characteristics, expressed as median and range of κ's between all sets of raters
| Lesion characteristics | Median κ between sets of raters | Range of κ's |
|---|---|---|
| General characteristics | ||
| Lesion size >3 cm | 0.52 | 0.18–0.70 |
| Tissue involvement | ||
| Juxtacortical WM | 0.72 | 0.44–0.87 |
| Periventricular WM | 0.59 | 0.47–0.84 |
| Cortical GM | 0.22 | 0.13–0.35 |
| Lesion appearance | ||
| Focal lesion appearance | 0.56 | 0.38–0.82 |
| Lesion borders | ||
| Lesion border towards WM | 0.19 | −0.24–0.66 |
| Lesion border towards GM | 0.091 | −0.092–0.25 |
| Specific PML characteristics | ||
| Presence of punctate T2 lesions | 0.57 | 0.49–0.67 |
| MRI sequences and contrast enhancement | ||
| Presence of contrast enhancement | 0.78 | 0.55–0.87 |
FLAIR, fluid-attenuated inversion recovery; GM, grey matter; PML, progressive multifocal leukoencephalopathy; WM, white matter.