Table 4

Outcomes for people with dementia after 12 months: means and differences adjusted for covariates and the other intervention

Measure	Data set	Missing (N=241)	CSP	No CSP	MD	95% CI of MD	Significance level	RYCT	No RYCT	MD	95% CI of MD	Significance level	Significance level of interaction
QoL-AD self-reported*	Original	101	37.85	37.93	−0.0820	(−1.70 to 1.56)	0.92	38.14	37.63	0.510	(−1.17 to 2.08)	0.58	0.51
QoL-AD self-reported*	Imputed	0	36.43	36.59	−0.162	(−1.87 to 1.54)	0.85	36.86	36.16	0.702	(−1.05 to 2.45)	0.43	0.80
QoL-AD proxy reported*	Original	22	28.78	28.97	−0.200	(−1.44 to 1.05)	0.76	28.84	28.91	−0.0620	(−1.33 to 1.20)	0.92	0.02
QoL-AD proxy reported*	Imputed	0	28.50	28.49	0.050	(−1.21 to 1.31)	0.94	28.52	28.47	0.0660	(−1.17 to 1.30)	0.92	0.04
DEMQOL self-reported*	Original	103	96.65	94.11	2.54	(−0.67 to 5.74)	0.12	95.29	95.47	−0.173	(−3.35 to 3.00)	0.92	0.14
DEMQOL self-reported*	Imputed	0	93.99	90.87	3.12	(−0.27 to 6.51)	0.07	92.19	92.67	−0.488	(−4.17 to 3.20)	0.80	0.20
DEMQOL proxy reported*	Original	24	92.41	95.59	−3.18	(−6.15 to −0.22)	0.04	93.99	94.00	0.00600	(−2.97 to 2.98)	0.99	0.08
DEMQOL proxy reported*	Imputed	0	92.22	95.11	−2.90	(−5.88 to 0.08)	0.06	93.49	93.84	−0.348	(−3.46 to 2.76)	0.83	0.20
EQ-5D self-reported utility*	Original	121	0.76	0.82	−0.07	(−0.17 to 0)	0.31	0.82	0.77	0.05	(−0.05 to 0.15)	0.24	0.22
EQ-5D self-reported utility*	Imputed	0	0.75	0.84	−0.09	(−0.17 to −0.01)	0.11	0.80	0.79	0.03	(−0.07 to 0.13)	0.54	0.11
ED-5D self-reported general health*	Original	121	74.80	72.85	1.95	(−6.75 to 2.81)	0.51	72.95	74.70	1.74	(−6.91 to 2.52)	0.78	0.49
ED-5D self-reported general health*	Imputed	0	74.38	72.82	1.57	(−6.98 to 2.27)	0.72	72.48	74.72	2.24	(−6.24 to 3.25)	0.61	0.32
HADS total	Original	107	7.16	7.29	−0.132	(−1.87 to 1.60)	0.88	7.40	7.06	0.338	(−1.37 to 2.05)	0.70	0.21
HADS total	Imputed	0	9.27	9.42	−0.144	(−1.77 to 1.49)	0.86	9.49	9.21	0.280	(−1.18 to 1.74)	0.71	0.68
ADCS-ADL*	Original	68	40.70	42.79	−2.08	(−5.52 to 1.36)	0.24	40.18	43.31	−3.14	(−6.56 to 0.28)	0.07	0.02
ADCS-ADL*	Imputed	0	35.30	37.47	−2.18	(−6.07 to 1.71)	0.27	35.16	37.61	−2.45	(−5.95 to 1.06)	0.17	0.07
NPI	Original	25	24.72	24.09	0.630	(−4.36 to 5.62)	0.81	25.43	23.38	2.05	(−2.98 to 7.07)	0.43	0.16
NPI	Imputed	0	27.16	28.37	−1.20	(−6.64 to 4.23)	0.66	27.88	27.65	0.236	(−4.83 to 5.30)	0.93	0.40
QCPR total*	Original	104	60.50	59.66	0.841	(−1.22 to 2.90)	0.43	59.98	60.17	−0.196	(−2.22 to 1.83)	0.85	0.94
QCPR total*	Imputed	0	57.22	57.13	0.0880	(−2.71 to 2.88)	0.95	56.88	57.47	−0.598	(−2.61 to 1.41)	0.56	0.86

Covariates: baseline and MMSE scores, participant gender, kinship and centre (random effect).
* Higher scores are better.
ADCS-ADL, Alzheimer's Disease Cooperative Study—Activities of Daily Living; DEMQOL, quality of life for people with dementia; EQ-5D, EuroQol 5 dimensions; HADS, Hospital Anxiety and Depression Scale; MMSE, mini-mental state examination; NPI, neuropsychiatric inventory; QCPR, Quality of Caregiver–Patient Relationship; QoL-AD, Quality of Life in Alzheimer's Disease Scale.