Outcomes for family carers after 12 months: means and differences adjusted for covariates and the other intervention
Measure | Data set | Missing (N=241) | CSP | No CSP | MD | 95% CI of MD | Significance level | RYCT | No RYCT | MD | 95% CI of MD | Significance level | Significance level of interaction |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SF12 MCS* | Original | 0 | 41.56 | 41.05 | 0.517 | (−1.28 to 2.32) | 0.57 | 41.36 | 41.25 | 0.105 | (−1.72 to 1.93) | 0.91 | 0.74 |
Imputed | 0 | 41.56 | 41.05 | 0.517 | (−1.28 to 2.32) | 0.57 | 41.36 | 41.25 | 0.105 | (−1.72 to 1.93) | 0.91 | 0.74 | |
SF12 PCS* | Original | 0 | 43.86 | 43.25 | 0.613 | (−1.23 to 2.46) | 0.52 | 43.34 | 43.77 | −0.428 | (−2.29 to 1.43) | 0.65 | 0.98 |
Imputed | 0 | 43.86 | 43.25 | 0.613 | (−1.23 to 2.46) | 0.52 | 43.34 | 43.77 | −0.428 | (−2.29 to 1.43) | 0.65 | 0.98 | |
EQ-5D utility* | Original | 6 | 0.77 | 0.72 | 0.0513 | (−0.02 to 0.13) | 0.13 | 0.73 | 0.76 | −0.0250 | (−0.10 to 0.05) | 0.52 | 0.79 |
Imputed | 0 | 0.77 | 0.71 | 0.0574 | (−0.02 to 0.13) | 0.14 | 0.72 | 0.75 | −0.0310 | (−0.11 to 0.05) | 0.43 | 0.70 | |
EQ-5D self-rated global health* | Original | 6 | 70.72 | 69.34 | 1.38 | (−3.04 to 5.80) | 0.32 | 70.17 | 69.90 | 0.274 | (−4.16 to 4.70) | 0.87 | 0.34 |
Imputed | 0 | 69.73 | 69.35 | 0.384 | (−4.20 to 4.96) | 0.87 | 70.00 | 69.08 | 0.915 | (−3.65 to 5.48) | 0.69 | 0.27 | |
HADS anxiety | Original | 3 | 6.83 | 7.22 | −0.389 | (−1.33 to 0.56) | 0.22 | 7.19 | 6.85 | 0.336 | (−0.61 to 1.28) | 0.51 | 0.38 |
Imputed | 0 | 6.91 | 7.26 | −0.33 | (−1.31 to 0.60) | 0.47 | 7.23 | 6.93 | 0.298 | (−0.65 to 1.25) | 0.54 | 0.29 | |
HADS depression | Original | 3 | 5.93 | 5.96 | −0.0254 | (−0.90 to 0.85) | 0.84 | 5.93 | 5.96 | −0.0250 | (−0.91 to 0.86) | 0.94 | 0.71 |
Imputed | 0 | 5.99 | 5.97 | 0.0144 | (−0.85 to 0.88) | 0.97 | 5.95 | 6.02 | −0.0700 | (−0.95 to 0.81) | 0.88 | 0.65 | |
PANAS positive affectivity* | Original | 4 | 30.59 | 30.37 | 0.226 | (−1.23 to 1.68) | 0.77 | 31.02 | 29.94 | 1.07 | (−0.40 to 2.56) | 0.15 | 0.93 |
Imputed | 0 | 30.47 | 30.30 | 0.163 | (−1.29 to 1.62) | 0.83 | 30.85 | 29.92 | 0.936 | (−0.55 to 2.42) | 0.22 | 0.93 | |
COPE PAC* | Original | 24 | 12.14 | 12.26 | −0.116 | (−0.64 to 0.41) | 0.70 | 12.26 | 12.14 | 0.114 | (−0.41 to 0.64) | 0.65 | 0.79 |
Imputed | 0 | 12.13 | 12.11 | 0.0125 | (−0.54 to 0.56) | 0.96 | 12.16 | 12.08 | 0.0784 | (−0.45 to 0.61) | 0.77 | 0.93 | |
Carer distress NPI-D | Original | 37 | 11.94 | 9.51 | 2.435 | (0.14 to 4.73) | 0.04 | 10.58 | 10.87 | −0.294 | (−2.58 to 1.99) | 0.73 | 0.10 |
Imputed | 0 | 12.63 | 10.82 | 1.819 | (−0.46 to 4.10) | 0.12 | 11.68 | 11.77 | −0.0851 | (−2.28 to 2.10) | 0.94 | 0.40 | |
Personal growth* | Original | 5 | 12.03 | 12.43 | −0.396 | (−0.98 to 0.19) | 0.18 | 12.41 | 12.05 | 0.360 | (−0.23 to 0.95) | 0.26 | 0.23 |
Imputed | 0 | 12.03 | 12.44 | −0.412 | (−1.00 to 0.18) | 0.17 | 12.42 | 12.05 | 0.369 | (−0.22 to 0.96) | 0.22 | 0.23 | |
QCPR warmth* | Original | 24 | 31.36 | 31.27 | 0.0936 | (−1.11 to 1.30) | 0.82 | 31.72 | 30.91 | 0.819 | (−0.40 to 2.04) | 0.17 | 0.69 |
Imputed | 0 | 31.32 | 31.06 | 0.260 | (−0.99 to 1.50) | 0.68 | 31.63 | 30.74 | 0.892 | (−0.33 to 2.12) | 0.15 | 0.76 | |
QCPR absence of criticism and conflict* | Original | 24 | 22.23 | 21.45 | 0.778 | (−0.28 to 1.84) | 0.15 | 22.19 | 21.49 | 0.704 | (−0.35 to 1.76) | 0.19 | 0.97 |
Imputed | 0 | 22.08 | 20.97 | 1.107 | (0.00 to 2.21) | 0.05 | 22.02 | 21.04 | 0.981 | (−0.15 to 2.11) | 0.09 | 0.76 | |
QCPR total* | Original | 24 | 53.60 | 52.70 | 0.903 | (−1.03 to 2.83) | 0.33 | 53.89 | 52.40 | 1.493 | (−0.44 to 3.42) | 0.12 | 0.81 |
Imputed | 0 | 53.41 | 52.00 | 1.416 | (−0.47 to 3.30) | 0.14 | 53.64 | 51.77 | 1.869 | (−0.02 to 3.75) | 0.05 | 0.84 | |
Loneliness | Original | 4 | 2.68 | 2.51 | 0.168 | (−0.32 to 0.66) | 0.61 | 2.47 | 2.71 | −0.244 | (−0.73 to 0.24) | 0.31 | 0.52 |
Imputed | 0 | 2.72 | 2.53 | 0.187 | (−0.31 to 0.68) | 0.46 | 2.49 | 2.76 | −0.267 | (−0.76 to 0.22) | 0.29 | 0.40 |
Covariates: baseline score, carer gender, kinship and centre (random effect).
*Higher scores are better.
COPE, Carers of Older People in Europe; EQ-5D, EuroQol 5 dimensions; HADS, Hospital Anxiety and Depression Scale; MCS, mental component score; NPI-D, Neuropsychiatric Inventory Distress Scale; PAC, Positive Aspects of Caring; PANAS, Positive and Negative Affect Schedule; PCS, Physical Component Score; QCPR, Quality of Caregiver–Patient Relationship; SF, short form.