Effects of covariates on time from diagnosis to respiratory involvement: univariate analyses
| Variable | Onset-site group | Coefficient | 95% CI | p Value |
|---|---|---|---|---|
| Age at symptom onset (years) | Bulbar | −0.0235 | −0.030 to −0.017 | 1×10−12 |
| Limb | −0.0253 | −0.031 to −0.020 | 1×10−18 | |
| Diagnostic delay (months) | Bulbar | 0.226 | 0.11 to 0.35 | 3×10−4 |
| Limb | 0.166 | 0.07 to 0.26 | 9×10−4 | |
| Riluzole use | Bulbar | 0.328 | 0.15 to 0.51 | 3×10−4 |
| Limb | 0.408 | 0.22 to 0.60 | 2×10−5 | |
| Male gender | Bulbar | −0.068 | −0.25 to 0.12 | 0.5 |
| Limb | 0.007 | −0.18 to 0.19 | 0.9 |