Number of patients fulfilling the criteria and the sensitivity and specificity of each criterion or of combination of criteria for the discrimination between RRMS and AQP4-ab NMOSD
| Number of participants | Criterion (a): lesion adjacent to the body of a LV and inferior temporal lobe lesion | Criterion (b): U-fibre lesions | Criterion (c): Dawson's fingers | Full criteria (a, b or c) | |
|---|---|---|---|---|---|
| AQP4-ab NMOSD, n | 31 | 1 | 2 | 2 | 4 |
| RRMS, n | 44 | 32 | 13 | 36 | 40 |
| Sensitivity, % | – | 72.7 | 29.6 | 81.8 | 90.9 |
| Specificity, % | – | 96.8 | 93.6 | 93.6 | 87.1 |
| PPV, % | – | 97 | 86.7 | 94.7 | 90.9 |
| NPV, % | – | 71.4 | 48.3 | 78.4 | 87.1 |
NMOSD, neuromyelitis optica spectrum disorders; LV, lateral ventricle.