Table 2

Overlapping loci between FTD, PD and AD at a conjunction FDR<0.05

SNPPositionChrLocation; nearest geneAssociated phenotypeMin Conj FDRFTD p-valueAssociated phenotype p-valueDirection of effect
rs766488977 087 7044Intronic; SCARB2PD4.84E−021.75E−048.88E−04++++
rs926887732 431 1476Intergenic; HLA-DRAPD4.84E−021.04E−107.41E−04++++
rs676768116 030 77310Intronic; VWA2PD4.27E−023.12E−046.14E−04++++
rs1078435940 445 75012Intronic; SLC2A13PD3.26E−021.58E−047.47E−05++++
rs2893253107 067 20313Intergenic; EFNB2PD3.55E−022.02E−041.11E−04++++
rs19952844 843 13617Intronic; WNT3PD1.80E−024.09E−059.82E−16++++
rs135807143 803 18917Intronic; CRHR1PD2.02E−024.96E−057.76E−15++++
rs1296454356 543 09518Intronic; ZNF532PD2.73E−021.12E−043.08E−04++++
rs40550945 408 83619Intergenic; APOEAD5.22E−031.25E−056.16E−70++++
  • AD, Alzheimer's disease; FDR, false discovery rate; FTD, frontotemporal dementia; PD, Parkinson's disease.