bvFTD | ALS-FTD | χ2 | p Value | |||
% present | n | % present | n | |||
Behavioural features | ||||||
Socially inappropriate behaviour | 63 | 176 | 36 | 54 | 14.25 | <0.001*** |
Loss of decorum | 83 | 180 | 50 | 54 | 26.05 | <0.001*** |
Impulsivity | 40 | 174 | 21 | 52 | 6.08 | 0.015* |
Apathy | 86 | 182 | 71 | 51 | 2.55 | 0.120 |
Inertia | 40 | 181 | 7 | 54 | 21.02 | <0.001*** |
Economy of effort | 60 | 183 | 39 | 55 | 7.32 | 0.008** |
Emotional changes | ||||||
Reduced concern for others | 52 | 160 | 32 | 48 | 7.55 | 0.008** |
Diminished social interest | 67 | 167 | 54 | 50 | 4.95 | 0.031* |
Bland affect | 68 | 171 | 61 | 54 | 2.03 | 0.172 |
Reduced interpersonal warmth | 74 | 160 | 31 | 51 | 19.19 | <0.001*** |
Emotional lability | 5 | 184 | 29 | 53 | 27.91 | <0.001*** |
Insight | ||||||
Reduced emotional insight† | 87 | 172 | 88 | 53 | 0.67 | 0.304 |
Reduced cognitive insight | 82 | 172 | 75 | 53 | 2.84 | 0.111 |
Unconcern for illness† | 89 | 175 | 86 | 53 | 0.62 | 0.538 |
Stereotypies | ||||||
Simple repetitive behaviours | 38 | 182 | 29 | 55 | 1.60 | 0.263 |
Complex repetitive behaviours | 72 | 134 | 38 | 54 | 23.48 | <0.001*** |
Verbal stereotypies | 57 | 183 | 39 | 53 | 4.46 | 0.042* |
Clock-watching | 35 | 183 | 32 | 55 | 0.09 | 0.872 |
Eating behaviour | ||||||
Food fads | 62 | 173 | 38 | 48 | 8.20 | 0.004** |
Sweet food preference | 53 | 172 | 23 | 48 | 13.42 | <0.001*** |
Gluttony | 47 | 173 | 18 | 48 | 13.24 | <0.001*** |
Oral exploration of inedible objects† | 0.5 | 174 | 0 | 56 | 0.28 | 1.00 |
Neuropsychiatric features | ||||||
Hallucinations | 10 | 111 | 14 | 39 | 0.26 | 0.797 |
Delusions | 15 | 115 | 14 | 39 | 0.24 | 0.669 |
Obsessions/pathological preoccupations | 37 | 142 | 32 | 46 | 1.07 | 0.313 |
Bizarre/irrational beliefs or behaviour | 12 | 120 | 13 | 38 | 0.00 | 1.00 |
Somatic symptoms | 10 | 183 | 9 | 55 | 0.27 | 1.00 |
Depression | 8 | 168 | 20 | 51 | 6.78 | 0.013* |
*p<0.05; **p<0.01; ***p<0.001.
†Fisher’s exact statistic used as expected cell counts below 5.
ALS-FTD, behavioural variant frontotemporal dementia with amyotrophic lateral sclerosis; bvFTD, behavioural variant frontotemporal dementia.