Table 3

Multivariate linear regression models for cognitive symptom severity in patients with PD as assessed by MMSE scores

Independent variablesCoefficientSEr t p Value
Disease duration (years)0.06120.0950.0970.6500.519
Age (years)−0.2230.056−0.512−4.003<0.001**
Gender (male)0.2081.4220.0220.1470.884
Plasma α-synuclein level−0.2260.096−0.331−2.3510.023*
  • In this model, the MMSE score of patients with PD was set as the dependent variable, with age, gender, disease duration and plasma level of α-synuclein set as independent variables. r: correlation coefficient based on the model of multiple linear regression; t: t value for the coefficient of each parameter in the model; p: for r or t; R2-adjusted=0.3004, p<0.001 for the model. *: statistically significant, p<0.05; **: p<0.01.

  • MMSE, Mini-Mental State Examination; PD, Parkinson’s disease.