Table 2

Multivariate linear regression models for motor symptom severity in patients with PD as assessed by UPDRS part III scores

Independent variablesCoefficientSEr t p Value
Disease duration (years)0.3610.1770.3032.0380.048*
Age (years)0.1730.1070.2461.6250.112
Gender (male)4.0212.6880.2281.4960.142
Plasma α-synuclein level0.2130.1760.1861.2130.232
  • In this model, the motor score of UPDRS (part III) in the on state was set as the dependent variable, with age, gender, disease duration and plasma level of α-synuclein set as independent variables. r: correlation coefficient based on the model of multiple linear regression; t: t value for the coefficient of each parameter in the model; p: for r or t; R2-adjusted=0.1998, p=0.01 for the model. *: statistically significant, p<0.05; **: p<0.01.

  • PD, Parkinson’s disease; UPDRS, Unified Parkinson’s Disease Rating Scale.