Associations of PBA (CNS-LS ≥13) and measures of depression reported on the same day
| 705 cases Median (IQR) or counts (%) | No PBA 502 cases | PBA 203 cases | p Value* | PBA Crying-predominant 105 cases | PBA Laughter-predominant 98 cases | p Value* | |
| PHQ-9 | 6 (3–10) | 5 | 8 | <0.0001 | 10 | 7 | <0.01 |
| PHQ-9<10 | 503 | 387 | 117 | 52 | 65 | ||
| PHQ-9≥10 | 202 (28.7%) | 116 (23.2%) | 86 (42.4%) | <0.0001 | 53 (50.5%) | 33 (33.7%) | <0.05 |
| No MDD | 550 | 404 | 146 | 68 | 78 | ||
| MDD | 100 (15.4%) | 48 (10.6%) | 52 (26.3%) | <0.0001 | 36 (34.6%) | 16 (17.0%) | <0.01 |
*Wilcoxon rank-sum test used to compare continuous variables and Pearson’s χ2 test used to compare categorical variables.
CNS-LS, Center for Neurologic Study-Lability Scale; MDD, major depressive disorder; PBA, pseudobulbar affect; PHQ-9, Patient Health Questionnaire.