Table 1

Mean (standard deviation) cortical volumes (whole brain and each hemisphere) as a percentage of total intracranial volume in the total FTD cohort and TDP-43 subset

Frontal Temporal Parietal Occipital Cingulate Insula
Total FTD cohort: whole brain
AA9.3 (0.9)6.1 (0.8)5.5 (0.4)4.4 (0.4)1.44 (0.14)0.69 (0.12)
AG/GG9.6 (1.0)6.3 (0.8)5.4 (0.6)4.4 (0.4)1.49 (0.14)0.73 (0.11)
Total FTD cohort: left hemisphere
AA4.6 (0.5)2.9 (0.5)2.7 (0.3)2.2 (0.2)0.68 (0.09)0.34 (0.06)
AG/GG4.8 (0.5)3.0 (0.5)2.7 (0.3)2.2 (0.2)0.72 (0.08)0.36 (0.06)
Total FTD cohort: right hemisphere
AA4.7 (0.5)3.2 (0.4)2.8 (0.2)2.2 (0.2)0.76 (0.08)0.36 (0.07)
AG/GG4.8 (0.6)3.2 (0.4)2.7 (0.3)2.2 (0.2)0.77 (0.09)0.37 (0.06)
TDP-43 subset: whole brain
AA9.4 (1.0)5.8 (0.9)5.4 (0.5)4.4 (0.4)1.42 (0.16)0.69 (0.08)
AG/GG9.8 (1.0)6.0 (0.9)5.5 (0.4)4.4 (0.3)1.49 (0.14)0.72 (0.10)
TDP-43 subset: left hemisphere
AA4.6 (0.5)2.7 (0.6)2.6 (0.3)2.2 (0.2)0.66 (0.10)0.33 (0.05)
AG/GG4.9 (0.5)2.8 (0.6)2.8 (0.3)2.2 (0.2)0.69 (0.08)0.35 (0.06)
TDP-43 subset: right hemisphere
AA4.8 (0.5)3.1 (0.4)2.8 (0.3)2.2 (0.2)0.76 (0.08)0.36 (0.05)
AG/GG4.9 (0.5)3.2 (0.4)2.8 (0.3)2.2 (0.1)0.79 (0.09)0.37 (0.05)
  • FTD,¬†frontotemporal dementia.