Baseline demographics and PD characteristics
| Variable | PD subjects (n=423) | Healthy controls (HC) (n=196) | p Value (PD vs HC) |
| Age | |||
| Mean (SD) | 61.7 (9.7) | 60.9 (11.2) | 0.34 |
| (Min, Max) | (33.5, 84.9) | (30.6, 83.7) | |
| Missing | 0 | 0 | |
| Age | |||
| <56 years | 115 (27.2%) | 55 (28.1%) | 0.65 |
| 56–65 years | 152 (35.9%) | 76 (38.8%) | |
| >65 years | 156 (36.9%) | 65 (33.2%) | |
| Missing | 0 | 0 | |
| Gender | |||
| Male | 277 (65.5%) | 126 (64.3%) | 0.77 |
| Female | 146 (34.5%) | 70 (35.7%) | |
| Missing | 0 | 0 | |
| Education | |||
| <13 years | 76 (18.0%) | 29 (14.8%) | 0.33 |
| 13–23 years | 344 (81.3%) | 166 (84.7%) | |
| >23 years | 3 (0.7%) | 1 (0.5%) | |
| Missing | 0 | 0 | |
| Ethnicity | |||
| Hispanic/Latino | 9 (2.1%) | 3 (1.5%) | 0.62 |
| Not Hispanic/Latino | 414 (97.9%) | 193 (98.5%) | |
| Missing | 0 | 0 | |
| Race | |||
| White | 391 (92.4%) | 182 (92.7%) | 0.85 |
| Black/African-American | 6 (1.4%) | 9 (4.6%) | |
| Asian | 8 (1.9%) | 1 (0.5%) | |
| Other | 18 (4.3%) | 4 (2.0%) | |
| Missing | 0 | 0 | |
| Family history of PD | |||
| Family members w/PD | 103 (24.4%) | 10 (5.1%) | <0.0001 |
| No family members w/PD | 319 (75.6%) | 186 (94.9%) | |
| Missing | 1 | 0 | |
| Disease duration (Mon.) | |||
| Mean (SD) | 6.7 (6.5) | N/A | N/A |
| (Min, Max) | (0.4, 35.8) | N/A | |
| Missing | 0 | N/A | |
| Age of PD onset | |||
| Mean (SD) | 59.6 (10.0) | N/A | N/A |
| (Min, Max) | (25.4, 83.0) | N/A | |
| Missing | 8 | N/A | |
| Side most affected | |||
| Left | 179 (42.3%) | N/A | N/A |
| Right | 234 (55.3%) | N/A | |
| Symmetric | 10 (2.4%) | N/A | |
| Missing | 0 | N/A | |
| MDS-UPDRS mean (SD) score and subscores | |||
| MDS-UDPRS total score | 32.4 (13.1) | 4.6 (4.4) | <0.0001 |
| MDS-UDPRS Part I score | 5.6 (4.1) | 2.9 (3.0) | |
| MDS-UDPRS Part II score | 5.9 (4.2) | 0.5 (1.0) | |
| MDS-UDPRS Part III score | 20.9 (8.9) | 1.2 (2.2) | |
| Missing | 1 | 1 | |
| Hoehn and Yahr | |||
| Stage 0 | 0 (0.0%) | 193 (99.0%) | <0.0001 |
| Stage 1 | 185 (43.7%) | 2 (1.0%) | |
| Stage 2 | 236 (55.8%) | 0 (0.0%) | |
| Stages 3–5 | 2 (0.5%) | 0 (0.0%) | |
| Missing | 0 | 1 | |
| Modified Schwab and England Activities of Daily Living Scale | |||
| Mean (SD) | 93.2 (5.9) | N/A | N/A |
| (Min, Max) | (70.0, 100.0) | N/A | |
| Missing | 0 | N/A | |
| TD/non-TD classification | |||
| TD | 299 (70.9%) | 26 (13.3%) | <0.0001 |
| Non-TD | 123 (29.1%) | 169 (86.7%) | |
| Missing | 1 | 1 | |
| PIGD score | |||
| Mean (SD) | 0.23 (0.2) | 0.02 (0.1) | <0.0001 |
| (Min, Max) | (0.0, 1.4) | (0.0, 0.8) | |
| Missing | 1 | 1 | |
| Tremor score | |||
| Mean (SD) | 0.49 (0.3) | 0.03 (0.1) | <0.0001 |
| (Min, Max) | (0.0, 1.8) | (0.0, 0.6) | |
| Missing | 1 | 1 | |
Report generated on data submitted as of 4 January 2016.
MDS-UPDRS, Movement Disorder Society Unified Parkinson’s Disease Rating Scale; PD, Parkinson’s disease; PIGD, postural instability gait disorder; TD, tremor dominant.