Characteristics of initially suspected amyotrophic lateral sclerosis cases finally diagnosed with other diseases
| Diagnosis | n | CSF CHIT1 (pg/mL) | Serum CHIT1 (pg/mL) | CSF NfL (pg/mL) | CSF pNfH (pg/mL) |
| Polyneuropathy | 13 | 2440* (890–14 280) | 32 900 (18 600–78 400) | 922 (216–3535) | 309† (63–1580) |
| Myopathy | 7 | 2440* (795–58 260) | 32 350* (25 350–54 950) | 1202 (406–9165) | 414† (62–2653) |
| Myositis | 5 | 3165 (795–9960) | 30 350 (13 850–123 400) | 923 (405–3266) | 374 (242–2096) |
| Hereditary spastic paraplegia† | 4 | 1725† (650–3990) | 17 800† (17 450–73 650) | 630 (168–937) | 177† (100–244) |
| Cramp-fasciculation syndrome | 4 | 1240 (281–14 130) | 26 350† (2810–40 400) | 595 (469–7622) | 252 (90–4160) |
| Chronic inflammatory demyelinating polyneuropathy | 3 | 8640 (1040–39 420) | n.a. | 5104† (3548–6660) | 1599† (1264–1934) |
| Somatization disorder | 4 | 2495 (4205–6020) | 34 125 (14 750–43 900) | 921 (338–1502) | 266 (93–225) |
| Anterior spinal artery syndrome | 1 | 7820 | 27 300 | 891 | 274 |
| Encephalitis | 1 | 2970 | n.a. | 3498 | 1293 |
| Myelitis | 1 | 1000 | 32 100 | 921 | 252 |
| Peroneal neuropathy | 1 | 15 270 | 46 350 | 1534 | 384 |
| Cervical myelopathy with radiculopathy | 1 | 30 820 | n.a. | 4380 | 1923 |
| Spinocerebellar ataxia | 1 | 1165 | 60 300 | 1161 | 799 |
*Two values missing
†One value missing
Given are median values and ranges.
CHIT1, chitotriosidase; NfL, neurofilament light chain; pNfH, phosphorylated neurofilament heavy chain.