Diagnosis | Pre-API (n=100) | Post-API (n=96)* |
SCI | 2 | 1 |
MCI | 22 | 23 |
MCI-AD | 9 | 6 |
AD | 56 | 43 |
Non-AD dementia | 11 | 23† |
Result | Number | |
API positive | 49 | |
Change in diagnosis(96) | 30 | |
Change in management (n=90) | 42 | |
ACE-I/memantine | 24 | |
Depression/behavioural treatment | 6 | |
Clinical trial | 2 | |
Other treatment§ | 3 | |
Further otherwise unplanned investigation | 7 |
*Four patients have had post the scan diagnosis documented yet.
†Statistical difference between pre-API and post-API; p=0.02.
§Ventriculoperitoneal shunt insertion (1), course of methyl prednisolone (1), donepezil stopped (1).
ACE-I, acetyl cholinesterase inhibitor; AD, Alzheimer’s disease; API, amyloid PET Imaging; MCI, mild cognitive impairment; SCI, subjective cognitive impairment.