Clinical and psychological data of current subjects
| Total (n=17) | High AS scores (n=10) | Low AS scores (n=7) | t | P values | HC (n=9) | |
| Clinical stage: AD (MCI) | 8 (9) | 6 (4) | 2 (5) | – | ||
| Age: mean (SD) | 70.7 (8.4) | 68.3 (10) | 74.1 (2.7) | −1.67 | 0.123 | 66.5 (6.2) |
| Years of schooling: mean (SD) | 12.2 (2.1) | 12.1 (2.1) | 12.4 (2.2) | −0.31 | 0.760 | 14.7 (2.0) |
| Sex: male (%) | 7 (41) | 2 (20) | 5 (71) | 0.058 | 7 (78) | |
| MMSE: mean (SD) | 21.4 (6.5) | 19.7 (6.0) | 23.7 (6.9) | −1.29 | 0.218 | 29.4 (0.7) |
| FAB: mean (SD) | 12.8 (3.5) | 11.7 (3.9) | 14.3 (2.2) | −1.74 | 0.103 | – |
| AS: mean (SD) | 14.1 (6.2) | 18.3 (1.6) | 8.0 (5.0) | 5.24 | 0.001* | – |
| GDS: mean (SD) | 3.8 (2.7) | 4.5 (2.4) | 2.7 (2.8) | 1.40 | 0.181 | – |
*P<0.05.
AD, Alzheimer’s disease; AS, Apathy Scale; FAB, frontal assessment battery; GDS, Geriatric Depression Scale; HC, cognitively healthy control; MCI, mild cognitive impairment; MMSE, Mini Mental State Examination.