Table 2

Median and IQR for serum tau and NfL concentrations in controls and patients with sCJD. Results for sCJD subgroups according to PRNP codon 129 genotype are also shown

Serum tau (pg/mL)Serum NfL (pg/mL)
nMedianIQRnMedianIQR
Controls24 1.56 1.32–1.9724 14.52 8.04–20.36
 sCJD
 Codon 129
All45 6.22 3.26–19.642 296.6 193–436
MM2119.67.82–47.319305.6206–480
MV153.272.71–5.1214215.1161–374
VV74.053.78–17.97350.1245–472
  • NfL, neurofilament light; sCJD, sporadic Creutzfeldt-Jakob disease.

  • Median results (shown in bold) and IQR for serum tau and NfL concentrations in controls and patients with sCJD. Results for sCJD subgroups according to  PRNP  codon 129 genotype are also shown.