Table 4

Number of AEDs and MBDs

UnadjustedAdjusted*
AEDs (n)nMBDs%OR95% CIOR95% CI
0112 77122942.011
132172.21.070.51 to 2.271.000.47 to 2.12
>13213.11.560.21 to 11.391.440.20 to 10.59
  • *OR adjusted for maternal age, education, smoking habit (5256—4.6% missing), diabetes, prescription of drugs belonging to X and D Food and Drug Administration pregnancy categories and fetal confounding pathologies of different aetiologies.

  • AED, antiepileptic drug; MBD, major birth defects.