Table 2

Correlations between metabolic index and patient information collected at the time of metabolic assessment

Characteristic at time of metabolic assessmentPearson
correlation, r
P values*
  Age (years)−0.19 (−0.4 to 0.07)0.16
  BMI0.16 (−0.11 to 0.40)0.24
  Fat mass (%)0.11 (−0.15 to 0.36)0.39
  Fat-free mass (kg)0.02 (−0.24 to 0.28)0.87
  Time since onset (months†)0.03 (−0.23 to 0.29)0.81
  Diagnostic delay (months)−0.05 (−0.22 to 0.30)0.74
Clinical scores
  ALSFRS-R−0.08 (−0.33 to 0.18)0.56
  FVC, % of predicted0.16 (−0.20 to 0.49)0.37
  UMN score0.05 (−0.22 to 0.32)0.69
  LMN score†0.47 (0.23 to 0.65)<0.01
Cognitive indices
  ECAS total score (n=24)0.20 (−0.22 to 0.56)0.34
  ACE III total score (n=38)0.41 (0.10 to 0.64)0.01
  • Data presented as mean (range).

  • *P value is based on Pearson correlation.

  • †Log-transformed value.

  • ACE III, Addenbrooke’s Cognitive Examination III, data corrected for items administered; ALSFRS-R, ALS Functional Rating Scale-Revised; BMI, body mass index; ECAS, Edinburgh Cognitive and Behavioural ALS Screen; FVC, forced vital capacity; LMN, lower motor neuron; UMN, upper motor neuron.