Correlations between metabolic index and patient information collected at the time of metabolic assessment
| Characteristic at time of metabolic assessment | Pearson correlation, r | P values* |
| Demographics | ||
| Age (years) | −0.19 (−0.4 to 0.07) | 0.16 |
| BMI | 0.16 (−0.11 to 0.40) | 0.24 |
| Fat mass (%) | 0.11 (−0.15 to 0.36) | 0.39 |
| Fat-free mass (kg) | 0.02 (−0.24 to 0.28) | 0.87 |
| Time since onset (months†) | 0.03 (−0.23 to 0.29) | 0.81 |
| Diagnostic delay (months) | −0.05 (−0.22 to 0.30) | 0.74 |
| Clinical scores | ||
| ALSFRS-R | −0.08 (−0.33 to 0.18) | 0.56 |
| FVC, % of predicted | 0.16 (−0.20 to 0.49) | 0.37 |
| UMN score | 0.05 (−0.22 to 0.32) | 0.69 |
| LMN score† | 0.47 (0.23 to 0.65) | <0.01 |
| Cognitive indices | ||
| ECAS total score (n=24) | 0.20 (−0.22 to 0.56) | 0.34 |
| ACE III total score (n=38) | 0.41 (0.10 to 0.64) | 0.01 |
Data presented as mean (range).
*P value is based on Pearson correlation.
†Log-transformed value.
ACE III, Addenbrooke’s Cognitive Examination III, data corrected for items administered; ALSFRS-R, ALS Functional Rating Scale-Revised; BMI, body mass index; ECAS, Edinburgh Cognitive and Behavioural ALS Screen; FVC, forced vital capacity; LMN, lower motor neuron; UMN, upper motor neuron.