Table 2

Binary logistic regression analysis of the risk factors for NMOSD-AQP4 compared with MS

WomenMen
OR* (95% CI)P valueOR* (95% CI)P value
BMInaive, one unit decrease1.20 (1.00 to 1.43)0.0460.8 (0.47 to 1.28)0.338
Age at onset (ref: <20)1 (reference)1 (reference)
20–291.09 (0.22 to 5.40)0.1350.05 (<0.001 to 4.50)0.201
30–391.3 (0.28 to 6.05)0.2140.13 (0.002 to 4.37)0.253
40–493.37 (0.58 to 19.63)0.5520.33 (0.002 to 31.18)0.621
50-15.67 (1.44 to 171.12)0.0313.42 (0.057 to 839.73)0.558
  • *Binary logistic regression (reference: MS). Control variables included BMI, age at onset (categorised every 10 years). BMInaive, which is measured within 1 month of their disease onset and measured before the use of steroid treatment.

  • BMInaive, body mass index is measured within 1 month of their disease onset and measured before the use of steroid treatment; NMOSD-AQP4, neuromyelitis optica spectrum disorder with aquaporin-4 immunoglobulin G.