Table 3

Longitudinal OCT results of patients with NMOSD and HCs.

	Absolute change in HC	Absolute change in Eyes^ON− Eyes^ON+		Longitudinal change in Eyes^ON− vs HC					Longitudinal change in Eyes^ON+ vs HC
	Mean±SD	Mean±SD	Mean±SD	B	SE	R² _marg	R² _cond	P values	B	SE	R² _marg	R² _cond	P values
GCIP (mm³)	0.00±0.01	−0.01±0.02	0.00±0.02	−0.003	0.002	0.123	0.995	0.044	8.8e⁻⁵	0.002	0.580	0.997	0.960
pRNFL (µm)	−0.61±2.00	−0.68±3.52	−0.94±3.09	−0.104	0.312	0.016	0.980	0.740	−0.113	0.257	0.454	0.995	0.663
INL (mm³)	0.00±0.01	0.00±0.01	0.00±0.01	−6.7e⁻⁵	0.001	0.019	0.957	0.947	−5.0e⁻⁵	0.001	0.019	0.960	0.960
FT (µm)	0.52±4.16	−0.32±4.94	2.74±11.4	−0.047	0.510	0.077	0.991	0.927	0.936	1.093	0.142	0.994	0.396
TMV (mm³)	0.00±0.02	−0.01±0.03	−0.01±0.03	−0.001	0.003	0.234	0.997	0.740	−0.003	0.003	0.442	0.999	0.380

B, estimate; Eyes ON⁻, patients with NMOSD without a history of ON; Eyes ON⁺, patients with NMOSD with a history of ON; FT, fovea thickness; GCIP, combined ganglion cell and inner plexiform layer; HC, healthy control; INL, inner nuclear layer; NMOSD, neuromyelitis optica spectrum disorders; OCT, optical coherence tomography; ON, optic neuritis; pRNFL, peripapillary retinal nerve fibre layer;TMV, total macular volume.