Prevalence of non-motor features among PD cases and controls
| Controls (n=6479) | PD cases (n=120) | Age-adjusted OR (95%CI) for PD, p values | |
| Age, years* | 73.6(5.6) | 73.7(5.3) | |
| pRBD 2012 (single screening question), % | 12.3 | 52.6 | 7.98(5.52to 11.53), p<0.0001 |
| pRBD 2014 (including additional four screening questions), % | 0.3 | 2.3 | 7.52(2.30to 24.60), p=0.0008 |
| Constipation, % | 21.3 | 57.2 | 4.93(3.36to 7.24), p<0.0001 |
| Hyposmia (B-SIT), % | 13.5 | 72.0 | 19.03(11.80to 30.68), p<0.0001 |
| Hyposmia (self-report), % | 12.5 | 61.0 | 10.90(7.30to 16.29), p<0.0001 |
| Taste problems (self-report), % | 2.6 | 14.4 | 6.27(3.59to 10.98), p<0.0001 |
| Impaired colour vision, % | 9.8 | 38.3 | 5.80(3.86to 8.71), p<0.0001 |
| Excessive daytime sleepiness, % | 19.9 | 62.4 | 6.68(4.54to 9.85), p<0.0001 |
| Body pain, % | 13.2 | 28.9 | 2.65(1.76to 4.00), p<0.0001 |
| Depressive symptoms, % | 11.1 | 32.8 | 3.90(2.62to 5.81), p<0.0001 |
Results are weighted using inverse-probability weights
*Mean (SD). Value is not weighted
PD, Parkinson’s disease; pRBD, probable rapid eye movement sleep behaviour disorder.