Demographic overview
| NMOSD | HC | |
| Subjects (N) | 51 | 28 |
| Number of eyes (N) | 94 | 56 |
| Sex (female in %) | 84.3 | 78.6 |
| Age at baseline (years, mean±SD) | 47.3±14.4 | 43.1±9.8 |
| F/U time (years, median (range)) | 2.3 (1.0–3.5) | 2.3 (1.0–3.3) |
| Disease duration at baseline (years, mean±SD) | 5.7±5.4 | – |
| EDSS at baseline (median (range)) | 3 (0–6) | – |
| Eyes with a history of ON (N (%)) | 34 (36.2%) | – |
| Time from last ON to baseline (months, median (range)) | 46 (5–263) | – |
| Patients with attacks during F/U (N (%)) | 7 (14%) | – |
Age (W=867, p=0.118) and sex (χ2=0.110, p=0.740) did not differ between patients with NMOSD and HCs.
EDSS, Expanded Disability Status Scale; F/U, follow-up; HC, healthy controls; N, number of patients; NMOSD, neuromyelitis optica spectrum disorders; ON, optic neuritis.