Baseline OCT results of patients with NMOSD and HCs.
| Baseline HC | Baseline NMOSD | Baseline EyesON- vs HC | Baseline EyesON+ vs HC | Baseline EyesON− vs EyesON+ | ||||||||
| Mean±SD | EyesON- mean±SD | EyesON+ mean±SD | B | SE | P values | B | SE | P values | B | SE | P value | |
| GCIP (mm3) | 0.63±0.04 | 0.59±0.06 | 0.43±0.12 | −0.04 | 0.01 | 0.002 | −0.19 | 0.02 | <2.0e−16 | −0.15 | 0.02 | 7.4e−12 |
| pRNFL (µm) | 98.5±9.2 | 96.7±11.9 | 67.0±24.2 | −2.51 | 2.59 | 0.330 | −30.22 | 4.60 | 5.0e−11 | −27.91 | 4.54 | 7.9e−10 |
| INL (mm3) | 0.27±0.03 | 0.27±0.03 | 0.28±0.04 | −0.01 | 0.01 | 0.340 | −0.010 | 0.01 | 0.250 | 0.013 | 0.01 | 0.054 |
| FT (µm) | 278±19 | 267±21 | 262±20 | −9.99 | 4.85 | 0.040 | −17.79 | 4.99 | 3.7e−4 | −6.25 | 1.64 | 1.3e−4 |
| TMV (mm3) | 2.37±0.10 | 2.25±0.15 | 2.11±0.19 | −0.14 | 0.03 | 6.1e−6 | −0.27 | 0.04 | 3.7e−12 | −0.11 | 0.02 | 1.0e−5 |
B, estimate; Eyes ON−, patients with NMOSD without a history of ON; Eyes ON+, patients with NMOSD with a history of ON; FT, fovea thickness; GCIP, combined ganglion cell and inner plexiform layer; HC, healthy control; INL, inner nuclear layer; NMOSD, neuromyelitis optica spectrum disorders; OCT, optical coherence tomography; ON, optic neuritis; pRNFL, peripapillary retinal nerve fibre layer; TMV, total macular volume.