Population | Outcome | Studies (n) | Statin patients | Control patients | Patients (n) | Patient-years of follow-up |
Systematic review | – | 51 | – | – | 1 324 450 | 4 098 285 |
Meta-analysis | – | 43 | 84 356 | 94 597 | 178 953 | 317 291 |
Previous intracerebral haemorrhage | Total | 15 | 7645 | 42 729 | 50 374 | 91 467 |
Recurrent ICH | 3 | 3052 | 20 643 | 23 695 | 62 930 | |
Ischaemic stroke | 1 | 45 | 48 | 93 | 456 | |
Any stroke | 1 | 45 | 48 | 93 | 456 | |
All-cause mortality | 15 | 57 189 | 32 787 | 89 976 | 87 954 | |
Poor functional outcome | 7 | 1942 | 7171 | 9113 | 5915 | |
Previous ischaemic stroke | Total | 29 | 76 711 | 51 868 | 128 579 | 225 824 |
ICH | 11 | 64 005 | 39 520 | 103 525 | 210 509 | |
Recurrent ischaemic stroke | 3 | 40 808 | 12 354 | 53 162 | 50 870 | |
Any stroke | 7 | 41 643 | 13 617 | 55 260 | 59 078 | |
All-cause mortality | 13 | 51 500 | 23 148 | 74 648 | 43 568 | |
Poor functional outcome | 19 | 15 858 | 18 842 | 34 700 | 31 907 |
ICH, intracerebral haemorrhage.