Table 1

Total number of newly enrolled patients with amyotrophic lateral sclerosis (ALS) and incidence rates per 100 000 inhabitants in Korea (2011–2015)

Parameters at first diagnosisTotal number (%) of new patients with ALS*Use of riluzole %Tracheostomy %Incidence
(per 105)†
95% CI
Age
 <40140 (4.6)35.710.70.110.07 to 0.15
 40–49335 (11.0)60.916.40.760.58 to 0.94
 50–59782 (25.6)58.220.62.041.72 to 2.35
 ≥601792 (58.8)51.621.74.293.85 to 4.74
Sex
 Male1878 (61.6)51.821.51.471.32 to 1.62
 Female1171 (38.4)56.418.40.920.80 to 1.04
Income‡
 High1088 (35.7)53.322.31.301.13 to 1.48
 Middle1174 (38.5)56.020.41.010.88 to 1.14
 Low787 (25.8)50.317.31.411.19 to 1.63
Region
 Seoul city§601 (19.7)55.921.81.190.97 to 1.40
 Metropolitan¶707 (23.2)54.521.81.090.91 to 1.27
 Other areas**1741 (57.1)52.419.21.251.11 to 1.38
 Total3049 (100.0)53.620.31.201.10 to 1.29
 adjusted incidence††0.880.81 to 0.95
Age at diagnosis (mean±SD)61.4±12.4
Male:female ratio1.60
  • *5 years (2011–2015) total number of new patients.

  • †Crude incidence rate per 100 000 inhabitants.

  • ‡Income-based insurance contributions.

  • §Seoul metropolitan city.

  • ¶Other metropolitan cities.

  • **Non-metropolitan area.

  • ††Age-adjusted incidence (per 100 000 inhabitants) using WHO (2000–2025) world standard population.