Table 4

Association of EDSS and MSSS by allergy type

VariablesEDSS*MSSS†
OR95% CIP valuesEstimate95% CIP values
Any allergy vs NKA
 Unadjusted1.00(0.821 to 1.225)0.9747−0.039(−0.193 to 0.116)0.6253
 Adjusted1.20(0.980 to 1.478)0.07710.058(−0.074 to 0.191)0.3865
Environmental allergy vs NKA
 Unadjusted0.94(0.756 to 1.168)0.5730−0.071(−0.239 to 0.097)0.4063
 Adjusted1.21(0.969 to 1.517)0.09200.077(−0.069 to 0.222)0.3008
Food allergy vs NKA
 Unadjusted0.97(0.733 to 1.275)0.8114−0.017(−0.230 to 0.196)0.8751
 Adjusted1.16(0.869 to 1.547)0.31350.075(−0.105 to 0.256)0.4137
Drug allergy vs NKA
 Unadjusted1.10(0.884 to 1.368)0.3929−0.020(−0.189 to 0.149)0.8143
 Adjusted1.29(1.026 to 1.618)0.02940.088(−0.056 to 0.231)0.2320
  • *The multivariate model adjusted for sex, age at symptom onset, race (non-white vs white), disease category (progressive vs relapsing), percentage of time on disease-modifying therapy (DMT), and disease duration (DD).

  • †The multivariate model adjusted for sex, age at symptom onset, race (non-white vs white), disease category (progressive vs relapsing), and percentage of time on DMT. DD was used as the offset parameter.

  • EDSS, expanded disability status scale; MSSS, multiple sclerosis severity score; NKA, no known allergy.