Table 3

Association of the DRB1*16:02-DQA1*01:02 haplotype with anti-NMDAR encephalitis

CombinationPatients (n=61×2)Controls (n=571×2)OR (95% CI)P valuepadj
PositiveNegativePositiveNegative
DRB1*16:02+DQA1*01:02+ 175410510883.09 (1.65 to 5.52)0.000270.00108
DRB1*16:02+DQA1*01:02 1112111419.37 (0.11 to 733.03)0.183750.24501
DRB1*16:02DQA1*01:02+ 23173999691.26 (0.76 to 2.02)0.312900.31291
DRB1*16:02DQA1*01:02 81914411280.74 (0.55 to 0.99)0.038780.07757
  • P values were adjusted for multiple testing with false discovery rate (FDR) step-up method.

  • anti-NMDAR, anti-N-methyl-D-aspartate receptor.