Table 1

Demographic characteristics of study subjects, stratified by ‘No known allergy’ versus ‘Any allergy’

VariablesNo known allergyAny allergyP values
N427922
Age at last visit, mean (SD), years50.02 (12.31)49.41 (11.79)0.3832*
Age at first symptom, mean (SD), years34.12 (10.48)33.36 (10.13)0.2047*
Male, n (%)150 (35.13)194 (21.04)<0.0001†
Disease duration at last visit, mean (SD), years15.95 (10.91)16.09 (9.75)0.8103*
Disease category, n (%)
 Primary progressive MS25 (5.85)44 (4.77)0.0515†
 Secondary progressive MS85 (19.91)138 (14.97)
 Relapsing-remitting MS310 (72.60)731 (79.28)
 Progressive relapsing MS7 (1.64)9 (0.98)
Race, n (%)
 Asian4 (0.94)5 (0.54)0.1474‡
 Black or African American12 (2.81)38 (4.12)
 More than one race5 (1.17)24 (2.60)
 Native Hawaiian/Pacific Islander0 (0.00)2 (0.22)
 Unknown or not reported10 (2.34)13 (1.41)
 White396 (92.74)840 (91.11)
Ethnicity, n (%)
 Hispanic or Latino15 (3.51)44 (4.77)0.1797‡
 Not Hispanic or Latino407 (95.32)874 (94.79)
 Unknown or not reported5 (1.17)4 (0.43)
% time on DMT, mean (SD)48.29 (30.96)46.74 (29.38)0.3758*
EDSS at last visit, median (IQR)2.0 (3.0)2.0 (2.5)0.9748§
MSSS at last visit, median (IQR)1.70 (3.91)1.70 (3.10)0.5094§
  • *Means were compared with a two-sample t-test.

  • †Proportions were compared via a χ2 test for contingency tables.

  • ‡Proportions were compared via a Fisher’s exact test for contingency tables.

  • §Rank scores were compared via the Mann-Whitney U test.

  • DMT, disease-modifying therapy; EDSS, expanded disability status scale; MS, multiple sclerosis; MSSS, multiple sclerosis severity scale.