Table 1

Baseline characteristics of patients with Tourette syndrome receiving deep brain stimulation therapy

CharacteristicsPatients, number/total number with data (%)
Sex
 Male76/110 (69.1%)
 Female34/110 (30.9%)
Age, mean (SD, range) years
 At onset (n=59 patients)8.0 (3.8, 2.0–20.0)
 At diagnosis (n=17 patients)10.8 (5.6, 3.0–23.0)
 At surgery (n=110 patients)30.1 (10.9, 14.0–61.0)
Comorbidities
 Obsessive–compulsive behaviour56/80 (70.0%)
 Depression28/43 (65.1%)
 Anxiety23/39 (59.0%)
 Attention deficit disorder (or attention deficit hyperactivity disorder)8/24 (33.3%)
Clinical rating scale scores, mean (SD)
 Yale Global Tic Severity Scale (YGTSS) total score (n=110)69.4 (22.6)
 YGTSS motor score (n=61)22.6 (5.4)
 YGTSS phonic score (n=61)20.1 (8.2)
 YGTSS impairment score (n=48)40.7 (13.0)
 Yale-Brown Obsessive Compulsive Scale total score (n=68)18.5 (11.8)
Target brain region (bilateral)
 Centromedial (CM) thalamus51/110 (46.4%)
 Anterior globus pallidus internus (GPi)27/110 (24.5%)
 Posterior GPi20/110 (18.2%)
 Nucleus accumbens area/anterior limb of internal capsule (NA/ALIC)4/110 (3.6%)
 CM thalamus and anterior GPi3/110 (2.7%)
 CM thalamus and NA/ALIC5/110 (4.5%)