Volumes of the remaining thalamic nuclei in NMOSD patients and controls
Volume of thalamic nuclei | NMOSD | Controls | Comparison |
Medial geniculate nucleus (mm3), mean±SD | 233.6±34.1 | 233.2±37.5 | B=−0.49 (SE=5.18), p=0.925 |
Anterior nuclei (mm3), mean±SD | 177.9±41.9 | 189.4±45.1 | B=−11.69 (SE=6.32), p=0.068 |
Central nuclei (mm3), mean±SD | 276.5±60.2 | 273.1±56.5 | B=3.90 (SE=4.67), p=0.407 |
Lateral dorsal nucleus (mm3), mean±SD | 66.4±13.8 | 66.6±7.7 | B=−0.25 (SE=2.05), p=0.903 |
Lateral posterior nucleus (mm3), mean±SD | 521.4±77.2 | 547.0±68.2 | B=−27.1 (SE=11.34), p=0.020 |
Medial dorsal nucleus (mm3), mean±SD | 1129.2±186.1 | 1131.2±376.6 | B=3.43 (SE=32.77), p=0.917 |
Pulvinar (mm3), mean±SD | 2022.0±376.6 | 2028.4±377.1 | B=11.17 (SE=54.91), p=0.839 |
Ventral anterior nucleus (mm3), mean±SD | 647.7±95.4 | 670.6±111.2 | B=−22.32 (SE=14.19), p=0.120 |
Ventral lateral nucleus (mm3), mean±SD | 1007.2±114.5 | 1022.4±97.7 | B=−13.93 (SE=16.92), p=0.413 |
Note that all volumes are normalised using the SIENAX V-scaling factor and that the p values given are uncorrected for multiple comparisons. After correction for multiple comparisons, the lateral posterior nucleus was not smaller in NMOSD than controls (corrected p=0.180).
NMOSD, neuromyelitis optica spectrum disorders.