Table 2

GRADE summary of findings table

Certainty assessmentNo of patientsEffectCertainty
OutcomeNo of studiesStudy designRisk of biasInconsistencyIndirectnessImprecisionOther considerationsSurgeryEndovascularRelative
(95% CI)
Absolute
(95% CI)
Initial failure 32rCSSeriousNot seriousNot seriousNot seriousPossible publication bias6277530.15 (0.09–0.24)95 fewer per 1000 (83-107)Low
Late recurrence 22rCSSeriousNot seriousNot seriousNot seriousPossible publication bias4235250.19 (0.09–0.39)54 fewer per 1000 (48-62)Low
Neurological improvement 13rCSSeriousSeriousNot seriousSeriousPossible publication bias3874042.73 (1.67–4.48)130 more per 1000 (63-197)Very low
Complications 22rCSSeriousNot seriousNot seriousSeriousPossible publication bias2132021.78 (0.97–3.26)three more per 1000 (10 fewer to five more)Very low
Initial failure/late recurrence (Onyx vs NBCA) 9rCSSeriousNot seriousNot seriousSeriousPossible publication bias58753.87 (1.73–8.68)113 more per 1000 (77-148)Very low
  • NBCA, n-butyl 2-cyanoacrylate; rCS, retrospective case series.