Estimated change in prevalence per 100 000 persons per degree of latitude, unadjusted, adjusted for year of study and further adjustment for use of systematic diagnostic criteria and inclusion of possible cases
| Prevalence estimates with age-specific data | ||||
| All crude (n=880) Slope* (95% CI) | Crude (n=304) Slope* (95% CI) | Age-standardised (n=304) Slope* (95% CI) | ||
| Unadjusted | Original | 1.55 (1.28 to 1.83) | 0.81 (0.34 to 1.27) | 0.99 (0.47 to 1.50) |
| Current | 1.98 (1.68 to 2.27) | 1.01 (0.46 to 1.57) | 1.25 (0.65 to 1.86) | |
| Difference from adding new prevalence points | p = 0.10 | p = 0.012 | p = 0.005 | |
| Adjusted for prevalence year | Original | 4.64 (3.63 to 5.65) | 3.31 (1.79 to 4.83) | 3.60 (1.97 to 5.24) |
| Current | 5.27 (4.48 to 6.05) | 4.27 (2.71 to 5.82) | 4.34 (2.74 to 5.95) | |
| Difference from adding new prevalence points | p = 0.86 | p = 0.037 | p = 0.016 | |
| Fully adjusted model | Original | 4.09 (3.13 to 5.06) | 2.41 (1.16 to 3.66) | 2.68 (1.30 to 4.07) |
| Current | 5.03 (4.25 to 5.81) | 3.55 (2.19 to 4.90) | 3.64 (2.22 to 5.05) | |
| Difference from adding new prevalence points | p = 0.77 | p = 0.047 | p = 0.021 | |
Time adjustment is to the year 2018, in contrast to 2009 as in the previous paper.
Italicised figures are p-values for tests for difference between original and updated analyses.
*Slope is the prevalence increase per 100 000 population per degree of latitude increase.